Nanoparticle Imaging In
Hyperspectral Light Scatter
Nanoparticle Imaging in Hyperspectral Light-Scatter maps the spatial distribution of Nanoparticles, Nanowires, and Nanorods in a Heterogeneous Field of View |
- The PARISS® Analytical Hyperspectral Imaging system: is a microscope accessory for nanoparticle imaging, spectral segmentation, and mapping
- Live cells and tissue: Image single or thousands of nanoparticles, nanowires or nanorods in scattered light internalized in live, or prepared samples.
- NON DESTRUCTIVE! Benign illumination keeps live cells alive!
- No vacuum: Or special prep needed! Works with "wet" samples !
- Reveal the location: nano sized objects can be imaged and mapped, in color-codes, onto a grayscale image of the field of view - with absolute accuracy!
- Detect, analyze and characterize: Individual Nanoparticles imaged in scattered light can be analyzed in clumps, or aggregates in a heterogeneous field of view
- Work in LOW magnification: Observe a huge field of view in magnifications ranging from 10 to 100X
- Spectral identification of metals: Reveal the location of any material, especially metals, as a function of its spectrum in hyperspectral images
- Reveal size, shape and proximity: Spectral images in dark-field scatter often correlates with size shape and proximity especially in the presence of surface plasmon resonance (SPR)
- Low cost alternative: To SEM and TEM for many applications!
- Data is instrument independent
- Fluorescence: PARISS easily switches between light scatter and fluorescence
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Figure 1: Nanoparticle Imaging:
Bio conjugated Au nanoparticles internalized
within living cells in dark field |
Figure 2: Gold/Silver nanowire reveals subtle differences indicated by pseudo-color spectral classification codes |
Click here To view an
interactive nanoparticle imaging presentation
It is best if you run the presentation full screen , greater than 800x600 |
Nanoparticle Imaging in Hyperspectral
Light Scatter
is an effective means to obtain
High contrast and High Spectral Resolution
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1990-2010 LightForm, Inc all rights reserved |
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Nanoparticle imaging with hyperspectral imaging |