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"Nanoparticle Imaging with Hyperspectral Light Scatter"

Nanoparticle Imaging with Hyperspectral Light-Scatter maps the spatial distribution of Nanoparticles, Nanowires, and Nanorods in a heterogeneous field of view
  • Live cells and tissue: Hyperspectral nanoparticle imaging detects one or thousands of nanoparticles, wires or rods. Observe internalized particles within live or prepared samples over an unlimited field of view.
  • NON DESTRUCTIVE! Benign illumination keeps live cells alive!
  • No vacuum: Or special prep needed! Works with "wet" samples !
  • Reveal the location: Diverse nano objects are mapped in color onto a grayscale image of the field of view - with perfect accuracy!
  • Image, detect, analyze and characterize: Individual Nanoparticles, clumps, aggregates in a heterogeneous field of view
  • Work in LOW magnification: Observe a huge field of view in magnifications ranging from 10 to 100X
  • Spectral identification of metals: Reveal the location of any material, especially metals, as a function of its spectrum
  • Reveal size, shape and proximity: Spectral features often correlate with size shape and proximity especially when surface plasmon resonance (SPR) can be induced
  • Low cost alternative: To SEM and TEM for many applications!
  • The PARISS® Analytical Hyperspectral Imaging system: is a simple microscope accessory ideal for nanoparticle imaging
  • Fluorescence: PARISS easily "switches" between light scatter and fluorescence
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Nanoparticle Imaging in living cells
Nanoparticle imaging a gold nanowire
Nanoparticle Imaging presentation
Figure 1: Nanoparticle Imaging:
Bio conjugated Au nanoparticles internalized within living cells in dark field
Figure 2: Gold/Silver nanowire reveals subtle differences indicated by pseudo-color spectral classification codes

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Nanoparticle Imaging with the PARISS® Hyperspectral
light scatter system is an effective means to obtain
high contrast and high spectral resolution

 
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Nanoparticle imaging with hyperspectral imaging