The Detection and Spectral Characterization of Gold and Silver Nanoparticles, Nanowires and Nanorods with Surface Plasmon Resonance (SPR)

The PARISS® Hyperspectral Imaging System Mounts on a Microscope to Detect and Characterize Gold and Silver Nanoparticles in Surface Plasmon Resonance:

  • Live cells and tissue: Detect Single or thousands of gold, or silver nanoparticles, internalized in live or prepared samples.
  • NON DESTRUCTIVE! Benign illumination keeps live cells alive!
  • No vacuum: Or special prep needed! Works with "wet" samples !
  • Reveal the location: Diverse nanoparticles can be mapped in color onto a grayscale image of the field of view - with perfect accuracy!
  • Detect, analyse and characterize: Individual Nanoparticles, clumps, aggregates in a heterogeneous field of view
  • Work in LOW magnification: Observe a huge field of view in magnifications ranging from 10 to 100X
  • Spectral Characterization of SPR : Reveal the location of particle proximity as a function of spectral characteristics
  • Low cost alternative: To SEM and TEM for many applications!
  • The PARISS® Analytical Hyperspectral Imaging system: is a microscope accessory
  • Fluorescence: PARISS easily "switches" between (RAD-HSI) and fluorescence
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Nanoparticles in living cells
Nanowire detail
Nanoparticle presentation
Figure 1: Bio conjugated Au nanoparticles internalized within living cells in dark field
Figure 2: Gold/Silver nanowire reveals subtle differences indicated by pseudo-color spectral classification codes

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The PARISS® Analytical Hyperspectral
Imaging System works in
High Resolution, High Contrast, Surface Plasmon Resonance

 
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gold nanoparticles, gold nanowires, gold nanorods, surface plasmon resonance, hyperspectral imaging